Refractory Hypertension – Establishing the Truth Behind Your Illness

Unfortunately, the development of high blood pressure amongst Americans is extremely common. At least 1 of 3 Americans suffer with the disease and, more so, an astonishing number of others are unaware that they have it.

The American Heart Association recommends that every one has their blood pressure checked regularly in order to control the progression of the disease by way of treatment and lifestyle changes. Conversely, with the increasing severity of high blood pressure, refractory hypertension has become extremely prevalent.

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The number one objective for medical healthcare providers is to lower a hypertensive patients blood pressure levels. This is generally accomplished by prescribing antihypertensive drugs and offering lifestyle change recommendations. Yet, in the case of refractory hypertension, this has not proven effective.

There are at least 5% of hypertensive patients whose blood pressure remains elevated despite treatment compliance during hypertensive drug therapy; which may inevitably prove inadequate. The blood pressure simply remains uncontrollable to the extent that physicians must determine if there are any secondary causes for the chronic blood pressure elevation.

Certain environmental factors are known to induce resistant hypertension. Additionally, there may be pseudoresistance occurring or the patient may be suffering from a secondary form of hypertension such as renovascular hypertension. Environmental factors that potentially contribute to chronic elevated blood pressure are:

• obesity
• medical nonadherence
• excessive sodium intake
• suboptimal medical regimens

Pseudoresistant hypertension conditions are generally more associated with Stage 1 hypertension, yet it has the ability to manifest into refractory hypertension. Patients suffering with this condition (white-coat hypertension) do not encounter major organ damage. This is not characteristic of the disease, however. Finally, a secondary form of high blood pressure, specifically, the renovascular disease causes drug- resistant hypertension.

After the underlying cause is determined by medical healthcare provider, refractory hypertension is treated with combination therapy.  This therapy utilizes a combination of appropriate doses of a diuretic. The use of the combination therapy enhances blood pressure control. The objective is to avoid marked renal impairment which would require dialysis.

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