High Blood Pressure Remedy Report

Antioxidant Deficiency Linked To Pulmonary Hypertension

by Alvin

According to a recent study, the loss of antioxidants in the endothelial cells contributes to the loss of vasodilator effects. The cells function as a lining for the blood vessels in the lungs; thereby, ultimately, contributing to the development of pulmonary hypertension.

Facilitated by Serpil Erzurum of the Cleveland Clinic, the study evaluated the antioxidant activities in patients that suffered from idiopathic pulmonary arterial hypertension (IPAH). IPAH is a fatal disease that is characterized by a progressive increase in pulmonary artery pressure and vascular resistance.

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Details of Erzurum’s study indicated that the inactivation of the oxidants located inside the cell is the direct result of the cell’s defense against oxidants. The researchers also discovered from this study that the entire process may contribute to low levels of nitric acid. The nitric oxide is identified in IPAH and it is a fundamental component in the pathogenesis of pulmonary hypertension.

Conclusively, Dr. Erzurum declares that this study has significant potential to effectively and extensively benefit patients with IPAH. Dr. Erzurum states, “Antioxidant augmentation in patients might be used to increase nitric oxide vasodilator effects, reduce pulmonary artery pressures and potentially improve clinical outcomes.”

These findings can be found in the Clinical and Translational Science.

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